It would be difficult to name a more interesting scientific problem than that of knowledge of the brain, its overall mechanisms and its molecular nature. Rational management of the brain in the future and utilization of the principles of its functioning to construct various mechanisms to undergird present-day technological progress should follow as direct consequences of development of that sphere of knowledge.

This paper considers a possible national cultural and scientific synthesis which failed to take place: namely the integration of the Central European theoretical physicist Erwin Schrödinger into the primarily experimental orientations of the Oxford physics of the 1930s. We also consider the effect of the Oxford social and intellectual atmosphere generally, incluing the persistence of previous traditions which undervalued Science relative to the Arts, and University research relative to tutorial provision in the Colleges. The Oxford situation is then briefly contrasted (...) to that which Schrödinger later found in Dublin between 1939 and 1956, and which was to have a significantly more productive outcome. (shrink)

Differential scanning calorimetry (DSC) has been employed to investigate the glass transition activation energy E g, thermal stability and glass-forming ability (GFA) of Se90In10− x Sb x (x = 0, 2, 4, 6, 8, 10) chalcogenide glasses. DSC runs were performed at six different heating rates. Well-defined endothermic and exothermic peaks were obtained at glass transition and crystallization temperature. The dependence of glass transition temperature T g on heating rate (α), as well as composition of Sb, has been studied. From (...) the dependence of glass transition temperature on heating rate, the E g has been calculated on the basis of the Kissinger [Anal. Chem. 29 (1957) p.1702] and Moynihan [J. Phys. Chem. 78 (1974) p.267] models. Thermal stability has been monitored through the calculation of temperature differences T c–T g, the stability parameter S, and the enthalpy released during crystallization H c. The GFA has been investigated on the basis of the Hruby parameter H r, which is strong indicator of GFA. Results for GFA are in good agreement with fragility index F i calculations, indicating that Se90In6Sb4 is an excellent glass-former. (shrink)

An epistemic logic is built up on the basis of an analysis of two skeptical arguments. the method used is to first construct an inference relation appropriate to epistemic contexts and introduce "a knows that..." as an operator giving rise to sentences closed with respect to this new concept of inference. soundness and completeness proofs are provided using auxiliary three-valued valuations.

Desmosomes are junctions involved in intercellular adhesion of epithelial cells and hemidesmosomes are junctions involved in adhesion of epithelia to basement membranes. Both are characterised at the ultrastructural level by dense cytoplasmic plaques which are linked to the intermediate filament cytoskeleton of the cells. The plaques strongly resemble each other suggesting a relationship between the two kinds of junctions, as implied by their names. Recent characterisation of the molecular components of the junctions shows they are, in fact, quite unrelated implying (...) that structural similarity is fortuitous. The molecular biology raises many fascinating problems relating to their structure and function. (shrink)

Uneasy times such as the present are distinguished by the extreme indeterminacy and fuzziness of the language they use. But as a rule this is veiled over, not unsuccessfully, if often unconsciously and with self-deception. The concrete examples or "figures" of linguistic expression are quite diverse: they include the reduction of the conceptual structures of language to purely verbal constructions and schemata, the uncommonly frequent use of certain words and expressions, which creates the illusion that they are clear and well (...) defined, and much, much else. (shrink)

Pluralism is on everyone's lips these days. Only lazy people do not refer to it. Politicians and authorities on political affairs are particularly eager to talk about it. Not to be left behind are scholars who broaden pluralism to a philosophical methodological position that fits best the spirit of the times and the present historical situation. Some writers view pluralism as the most important discovery of the twentieth century, a further development of the Copernican revolution in philosophy.

The Vatican palimpsest omits the word enthymemate and leaves a lacuna, thus showing that the scribe found it written as Greek in his exemplar. Now A has been shown to belong to the fourth century, and therefore its authority must be greater than that of the other manuscripts available for this part of Gellius. The same problem occurs in 12.2.14, non pro enthymemate aliquo, where Hertz goes against the Greek of the manuscripts and adopts the reading of Carrio. Yet an (...) examination of the use of the Greek dative in Cicero's Letters will show that it can be used fully as the equivalent of a Latin ablative, can be governed by prepositions taking the ablative in Latin, and can be qualified by a Latin adjective in the ablative. (shrink)

The various papers and short "discussions" contained in this latest addition to the "Studies in Logic" series were presented at the 1965 International Colloquium in the Philosophy of Science, in London. Of the nine "problems" considered in this symposium, seven have directly to do with philosophy, one is an historical study of the origins of Euclid's axiomatics, and the last is an interesting—if one-sided—discussion of the "new math" controversy in the pre-college curriculum. Happily, this book demonstrates that the important issues (...) in the philosophy of mathematics somewhat outrun the usual ism-mongering debate between representatives of various schools. Unhappily, it also demonstrates that a good deal of undeserving material seems to find its way between the covers of scholarly books. After reading certain of the articles in this volume one is left with the feeling that the authors have not come to grips with the issues which they raise, that a lot of effort has been expended on peripheral matters, and that, in some instances, a sledge hammer has been brought down upon an egg. Abraham Robinson's article, "The Metaphysics of the Calculus," deals with a series of important linguistic and ontological problems concerning the foundations of analysis. Moreover, these are problems which can no longer be ignored, especially in view of the evolution of non-standard analysis. But, unfortunately, the interested reader would do far better to turn to Robinson's recent book on the subject, and pay special attention to the second, third, and last chapters therein. "On a Fregean Dogma" by Fred Sommers gives a rather curious non-quantificational algorithm for the monadic fragment of syllogistic. This Sommers does in the interest of "a conservative effort to restore categorical statements to predicative status." Despite the heat and the occasional interesting remarks which the discussion generated, one is inclined to ask, "So what?" The sequence of three papers by Mostowski, Bernays, and Körner is best considered as a group, since each of these is concerned with the philosophical significance of recent results in set theory and logic. Students of the philosophy of mathematics would do well to read this part of the book very carefully, although one wishes that the authors would elaborate a bit on their specific philosophical views. Finally, there is Georg Kreisel's difficult and amazing paper, "Informal Rigor and Completeness Proofs," in which is presented a mathematical treatment of the problem of selecting the primitive rules and concepts of mathematical systems. Kreisel's ideas are refreshing, unorthodox, dubious, and a genuine contribution to the philosophy of mathematics. In sum, this book is a mixed bag, uneven in the quality of its contents, but worth reading.—H. P. K. (shrink)

The critical reader who possesses the patience requisite for wading through this linguistic morass can expect to be rewarded with a number of interesting insights and observations, primarily concerning phenomenological aspects of science and scientific method. Sikora's argument is informed by a Thomist philosophy of science-especially as exemplified in the writings of Jacques Maritain. His task is an analysis of the distinction and relation between physical science and its philosophy—an interesting and important problem. But unfortunately as in steamship cruises to (...) exotic and far away lands, so also in philosophy: getting there is half the fun.—H. P. K. (shrink)

Childhood obesity is a serious problem for increasing numbers of children around the world. According to the International Obesity Task Force, 1 of 10 schoolaged children worldwide is overweight or obese, a number totaling 155 million; of these, 2-3% are obese. Prevalence is highest in the Americas and Europe, followed by the Near/Middle East, with smaller but growing numbers in the Asia-Pacific and Sub-Saharan regions of the world.In the United States, which provides the data for much of this report, prevalence (...) continues to rise. The most recent nationally representative data indicate that 33.6% of individuals aged 2-19 years were overweight and 17.1% were at risk for overweight in 2003-2004, compared to 28.2% and 13.9% in 1999-2000, respectively. In this age group, the prevalence of overweight or at risk for overweight was highest among Mexican Americans, followed by Non-Hispanic blacks and Non-Hispanic whites, and a higher percentage of males were overweight compared to females. (shrink)